TO THE ISSUE OF FORENSIC CHEMICAL ANALYSIS OF A NUMBER OF ANTIDIABETIC DRUGS

M.M. IBRAGIMOVA

Abstract

This study focuses on the development of methods for the isolation of a number of anti-diabetic drugs - sulfonylureas - glyburide, glimepiride, gliclazide, glipizide and gliquidone from biological specimens (blood, urine, and internal organs). Due to the fact that sulfonylureas have acidic properties, methods of isolation based on chloroform extraction from acidic solutions. As an elimination method thin-layer chromatography (TLC) is suggested. TLC, TLC in system of TOXI-LAB AB, UV-spectrophotometry were used for the detection of sulfonylureas